Viral vectors are a common tool for introducing new or corrected genes into human cells tor product cellular therapy products. Chimeric antigen receptor T (CAR T) cells require lentivirus to introduce the CAR gene into activated T cells. Lentiviral vectors have also been used for the treatment of hereditary disorders, such as severe combined immunodeficiency disorder (SCID) and Wiskott-Aldrich syndrome. Although lentiviral vectors are ideal for delivery and stable integration of genes of interest into the host cell genome, they potentially pose risks to human health, such as integration-mediated transformation and generation of a replication-competent lentivirus (RCL) capable of infecting non-target cells. In consideration of the latter risk, all cell-based products modified by lentiviral vectors and intended for patient use must be tested for RCL before treatment of the patient.

• Listing ID: 41905
• Country: USA
• City: New York

1. Check all listings by this user
2. Add to favourites
3. Report abuse

Contact details

Country: USA

City: New York

Shirley, NY 11967, USA11967 Show phone number6313868241 contact@creative-biogene.com https://qvirus.creative-biogene.com/

Contact this listing owner

Your Name*

Your E-mail Address*

Your Phone Number

Your Message*

Submit