HCN1 & HCN4
Businesses / Posted 3 months ago by Hannah Cole / 35 views
HCN1 & HCN4 belong to the ion channel family of hyperpolarization-activated cyclic nucleotide-gated (HCN) cation channels. Upon hyperpolarization, both generate a characteristic inward current which shows the typical properties of the conductance coined If in the heart and Ih in the brain.
HCN1 is the fastest activating channel with an activation constant τ in the range of 30 – 300ms, whereas HCN4 represents the most slowly activating isoform with τ between 300ms.
- Listing ID: 55059
- Country: USA
- City: New York